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A poor final visual acuity outcome (≤20/200) was found in 19 of 36 patients (53%) in the corticosteroid group and 2 of 16 patients (13%) in the PE group ( P = .008).

The gain in visual acuity was 20/200 in the corticosteroid group and 20/30 in the PE group ( P = .01). Results Final visual acuity was 20/400 in the corticosteroid group and 20/50 in the PE group ( P = .04). Retinal peripapillary fiber thickness was measured using optical coherence tomography. Visual acuity and visual field assessed with the Snellen scale and the logarithmic scale of the Early Treatment Diabetic Retinopathy Study were measured using standard automated perimetry and frequency doubling technology perimetry. The ophthalmologic examination was performed at least 6 months after optic neuritis treatment. Methods Thirty-six patients with optic neuritis were treated from January 1, 1995, through December 31, 2010, with pulsed intravenous corticosteroids and 16 with pulsed intravenous corticosteroids plus PE. Objective To assess the contribution of plasma exchange (PE) in association (add-on) with pulsed intravenous corticosteroids in acute optic neuritis of neuromyelitis optica (NMO) and limited forms of NMO. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.

Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.

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